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To investigate the impact of IKK2 inhibitor VIII (HY-13060, Medchem Categorical, Monmouth Junction, NJ) on OA development, MLI surgeries had been performed in 12-7 days-old C57BL/6 WT mice. The mice ended up injected with IKK2 inhibitor VIII (two mg/kg, IP) each individual alternate working day for 5 months. OARSI scoring was executed by blinded
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